hereditary cancer syndromes การใช้

Activating point mutations in RET can give rise to the hereditary cancer syndrome known as multiple endocrine neoplasia type 2 ( MEN 2 ).
An example of such a hereditary cancer syndrome is xeroderma pigmentosum, which causes the development of skin cancers in response to even minimal exposure to ultraviolet light.
For instance, at least 36 DNA repair enzymes, when mutationally defective in germ line cells, cause increased risk of cancer ( hereditary cancer syndromes ).
Von Hippel Lindau syndrome ( VHL ) is a dominantly inherited hereditary cancer syndrome predisposing to a variety of malignant and benign tumors of the eye, brain, spinal cord, kidney, pancreas, and adrenal glands.
Genetic counseling can occur before conception ( i . e . when one or two of the parents are carriers of a certain trait ) through to adulthood ( for adult onset genetic conditions, such as Huntington's disease or hereditary cancer syndromes ).